WebJul 1, 2012 · The presence of chromatin bridges ‘stuck’ in the division plane is sensed by the chromosomal passenger complex (CPC) component Aurora B kinase, triggering a checkpoint that delays abscission until the chromatin bridges have been resolved. Recent work has started to shed some light on the molecular mechanism by which the CPC … WebJan 8, 2024 · In this issue of the JCI, Das and colleagues report an association between early therapy-induced changes in circulating B cells and an increased risk of high-grade immune-related adverse events (IRAEs) in patients treated with checkpoint inhibitors that target cytotoxic T lymphocyte–associated antigen-4 (CTLA4) and programmed cell death ...
JCI - B cells as biomarkers: predicting immune checkpoint therapy ...
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Cambridge Checkpoint and Beyond - Biology Secondary 1 (Year 7) …
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