Cytoplasmic polyadenylation element

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August undefined, 2024

WebApr 23, 2004 · Cytoplasmic Polyadenylation Element (CPE)- and CPE-binding Protein (CPEB)-independent Mechanisms Regulate Early Class Maternal mRNA Translational … WebCytoplasmic polyadenylation, which is one mechanism of controlling translation, is driven by CPEB — a highly conserved, sequence-specific RNA-binding protein that binds to the cytoplasmic...

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WebThe cytoplasmic polyadenylation element (CPE) is a nucleotide sequence within the 3′ UTR of mRNAs which binds to the CPE-binding protein (CPEB). A highly conserved … WebDescription of elements in 3’ UTRs involved in translational regulation. Rounded rec-tangles, circles, along with the hexagon represent the various states. Each state is in turn a probabilistic model. Lines represent possible transitions from each probabilistic state. CPE: cytoplasmic polyadenylation element. Gap: nucleotide sequence gap. modbus station id

Cytoplasmic polyadenylation element - Wikipedia

WebResults: We show that cytoplasmic polyadenylation element-binding protein 4 (CPEB4), which controls the translation of specific mRNAs by modulating their poly (A) tails, is highly expressed in visceral fat of obese but not lean humans and rodents (mice and rats), where it orchestrates an essential post-transcriptional reprogramming for … WebFunction. Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation and early … WebCytoplasmic polyadenylation element-binding protein 1 Short names CPE-BP1; CPE-binding protein 1; mCPEB; mCPEB-1 Gene names Name Cpeb1 Synonyms Cpeb Organism names Organism Mus musculus (Mouse) Taxonomic … modbus sungrow

Post-transcriptional regulation of gene expression in innate

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WebJun 14, 2013 · The cytoplasmic polyadenylation element (CPE) recruits its binding protein CPEB1. 96 This binding can be stabilized, especially on noncanonical CPEs, by the recruitment of Pumilio (PUM2) to the Pumilio binding element (PBE) and protein–protein interactions between CPEB1 and PUM2. 99, 121 CPEB1 in turn interacts with the … WebThe cytoplasmic polyadenylation element binding (CPEB) proteins are sequence-specific mRNA binding proteins that control translation in development, health, and disease. modbus stationWebMar 2, 2009 · Translation in axons is required for growth cone chemotropic responses to many guidance cues. Although locally synthesized proteins are beginning to be identified, how specific mRNAs are selected for translation remains unclear. Control of poly(A) tail length by cytoplasmic polyadenylation element (CPE) binding protein 1 (CPEB1) is a … inmates charlotte county jail

"WebApr 4, 2024 · cytoplasmic polyadenylation element-binding protein 1, CPE-binding protein 1 GeneRIFs: Gene References Into Functions CPEB1 regulates the inflammatory immune response, phagocytosis, and alternative polyadenylation in microglia. MicroRNA-455-5p/CPEB1 pathway mediates Abeta-related learning and memory deficits in a … " - Cytoplasmic polyadenylation element

Cytoplasmic polyadenylation element

Specificity factors in cytoplasmic polyadenylation - PMC

WebNov 19, 2024 · Cytoplasmic polyadenylation elements (CPEs) are located in the 3-prime UTRs of hundreds of mRNAs involved in cell proliferation, chromosome segregation, and cell differentiation. CPEs function as docking sites for CPE-binding proteins (CPEBs), which can either repress or activate mRNA translation. CPEB4 activates mRNA translation by … WebMay 23, 2014 · The poly(A) signal and nearby U-rich or GU-rich downstream sequence elements are recognized by two multi-protein complexes — namely, cleavage and …

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WebCytoplasmic polyadenylation requires the RNA-binding proteins CPSF and CPEB, and can involve other RNA-binding proteins like Pumilio. [54] Depending on the cell type, the polymerase can be the same type of polyadenylate polymerase (PAP) that is used in the nuclear process, or the cytoplasmic polymerase GLD-2. [55] WebFeb 24, 2024 · In silico analysis of the tvcp12 3′-UTR showed the typical T. vaginalis elements for mRNA polyadenylation . Analysis of 25 nt downstream of the UAA stop codon of the tvcp12 mRNA by the mfold program [ 52 ] and the RNAfold software [ 53 ] predicted the formation of a stem-loop RNA secondary structure ( Figure 3 D).

WebMay 23, 2014 · A poly (A) signal and nearby U-rich or GU-rich downstream sequence elements (DSEs) are recognized by two multi-protein complexes — namely, cleavage and polyadenylation specificity factor (CPSF)... WebThe cytoplasmic polyadenylation element binding (CPEB) proteins are sequence-specific mRNA binding proteins that control translation in development, health, and disease. …

WebMar 29, 2024 · 21-Mar-2024 Summary This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to … WebNov 24, 2015 · The cytoplasmic polyadenylation (CP) element, Pumilio binding element, and hexanucleotide polyadenylation signal are among the best understood motifs involved in CP, and translational regulation of …

WebCytoplasmic polyadenylation, which is one mechanism of controlling translation, is driven by CPEB — a highly conserved, sequence-specific …

WebSequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation and early development. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR ( By similarity ). By … inmate scholars programThe cytoplasmic polyadenylation element (CPE) is a sequence element found in the 3' untranslated region of messenger RNA. While several sequence elements are known to regulate cytoplasmic polyadenylation, CPE is the best characterized. The most common CPE sequence is UUUUAU, though there are other variations. Binding of CPE binding protein (CPEB) to this region promotes the extension of the existing polyadenine tail and, in general, activation of the mRNA for protein … inmates clark countyWebNov 25, 2004 · Cytoplasmic polyadenylation depends on phosphorylation of CPEB, a protein that is bound to specific cytoplasmic polyadenylation elements (CPEs) in the 3' ends of transcripts regulated in this manner. In Xenopus , phosphorylation is mediated by the protein kinases Eg2 (known as Aurora A in the mouse) and Cdc2. modbus sur wifiWebMar 2, 2009 · The function of cytoplasmic polyadenylation in diverse systems from Xenopus oocyte maturation to synaptic plasticity suggested that this might be a … modbus stoppbitsWebJun 12, 2013 · Introduction. The cytoplasmic polyadenylation element binding protein (CPEB) regulates the expression of proteins required for both early development and synaptic plasticity. 1 Previous studies on oogenesis and embryonic development have shown that translational regulation is required to establish polarity leading to cellular … inmates crossword modbus tcp analogWebFeb 25, 2016 · Cytoplasmic Polyadenylation Element Binding proteins (CPEBs) are a family of polyadenylation factors interacting with 3'UTRs of mRNA and thereby regulating gene expression. Various functions of CPEBs in development, synaptic plasticity, and cellular senescence have been reported. modbus switch