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Unc-13 homolog a

Web21 Mar 2024 · UNC13A (Unc-13 Homolog A) is a Protein Coding gene. Diseases associated with UNC13A include Amyotrophic Lateral Sclerosis 1 and Lateral Sclerosis . Among its … Web1 Nov 1999 · The UNC-13 protein family has been suggested to be critical for synaptic vesicle dynamics based on its interactions with Syntaxin, Munc-18 and Doc 2alpha. We cloned the Drosophila homolog (Dunc-13) and characterized its function using a combination of electrophysiology and ultrastructural analyses.

UNC13A - Wikipedia

WebUNC13A, Munc13-1 Associated Syndromes - Chromosome Band 19p13.11 Associated Disorders - Relevance to Autism A de novo missense variant in the UNC13A gene (p.Pro814Leu) was identified in a 6-year-old diagnosed with ASD and comorbid ADHD and presenting with developmental delay and a dyskinetic movement disorder in Lipstein et … WebUNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of ... kjt building bathurst https://edgegroupllc.com

UNC13A/Munc13-1 Polyclonal Antibody (55053-1-AP)

Web21 Mar 2024 · UNC13C (Unc-13 Homolog C) is a Protein Coding gene. Among its related pathways are Synaptic vesicle pathway . Gene Ontology (GO) annotations related to this … Web26 Oct 2024 · This gene encodes a member of the UNC13 family. UNC13 proteins bind to phorbol esters and diacylglycerol and play important roles in neurotransmitter release at … WebOrthologous to human UNC13A (unc-13 homolog A); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide. Type: protein-coding RefSeq Status: VALIDATED: Previously known as: Munc13-1; protein unc-13 homolog A; unc-13 homolog A (C. … kjt faith temporary agency

Unc-13 homolog A (UNC13A) SpringerLink

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Unc-13 homolog a

UNC13A Result Summary BioGRID

Web2410078G03Rik; KIAA1032; Munc13-1; Protein unc-13 homolog A; unc-13 homolog A; unc-13 homolog A (C. elegans); unc13a View less Disclaimer. Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have ... WebProtein unc-13 homolog B; Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP).

Unc-13 homolog a

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Web25 Jan 2012 · Interacts with RIMS1 which recruits UNC13A to the active zone. Forms homodimers via its first C2 domain. Also interacts via this domain with the zinc finger … WebProtein unc-13 homolog C. UNC13C. Identifiers. Aliases. UNC13C, unc-13 homolog C. External IDs. OMIM: 614568 MGI: 2149021 HomoloGene: 45443 GeneCards: UNC13C. …

Webunc-13 homolog A (C. elegans) UNC13A; Background. UNC13A (UNCoordinated 13A; also Munc13-1) is a 190‑210 kDa member of the UNC-13 family, C2 domain protein superfamily of molecules. It is expressed at synaptic junctions, particularly those involved in GABA, acetylcholine and glutamine transmission, and appears to be necessary for ... WebUNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A)) Alternative Name Munc 13-1 ( UNC13A Products ) Synonyms Munc13-1 antibody, Unc13h1 antibody, 2410078G03Rik antibody, unc-13 homolog A antibody, unc-13 homolog A (C. elegans) antibody, Unc13a antibody, UNC13A antibody Pathways Skeletal Muscle Fiber Development, Synaptic …

Web5 Jul 2004 · A rare disorder characterized by immune dysregulation with hypercytokinemia, defective function of natural killer cell, and massive infiltration of several organs by … Web1 Jun 2003 · Protein unc-93 homolog A. Short names. HmUnc-93A; Unc-93A. Gene names. Name. UNC93A. Organism names. Organism. Homo sapiens (Human) Taxonomic identifier. 9606 NCBI. Taxonomic lineage. Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > …

Web13 Nov 2007 · Protein unc-13 homolog B Gene UNC13B Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 1591 Protein existence Evidence at …

Web29 Mar 2024 · UNC13A variant rs12608932 is associated with increased risk of amyotrophic lateral sclerosis and reduced patient survival: a meta-analysis. Yang B, et al. Neurol Sci, … kjt photography tucsonWeb19 Nov 2024 · Here, we identified unc-13 homolog D (UNC13D) as a direct, autophagy-related gene target of miR-517a, leading to repression of UNC13D. In line with the antiviral activity of miR-517a, silencing UNC13D suppressed replication of vesicular stomatitis virus (VSV), whereas overexpression of UNC13D increased VSV levels, suggesting a role for … recursion example in jsThis gene encodes a member of the UNC13 family. UNC13A plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity … See more Unc-13 homolog A (C. elegans) is a protein that in humans is encoded by the UNC13A gene. See more Several conserved domains have been found in UNC13A. These conserved domains include three C2 domains. One C2 domain is … See more UNC13A has been shown to interact with: • STX1A, • STX1B1, • DOC2A, • BSN, See more • Augustin I, Rosenmund C, Südhof TC, Brose N (July 1999). "Munc13-1 is essential for fusion competence of glutamatergic … See more UNC13A is localized to the active zone of presynaptic density. It is translocated to the plasma membrane in response to phorbol ester See more Single nucleotide polymorphisms in this gene may be associated with sporadic amyotrophic lateral sclerosis. This single nucleotide polymorphism has been discovered on chromosome 19. This variation of the single nucleotide involving UNC13A has also … See more recursion examples in pythonWeb30 Apr 2024 · UNC13A (unc-13 homolog A) EnsemblGeneIds (GRCh38): ENSG00000130477 EnsemblGeneIds (GRCh37): ENSG00000130477 OMIM: 609894, Gene2Phenotype UNC13A is in 5 panels Reviews (2) Details History 2 reviews Louise Daugherty (Genomics England Curator) Red List (low evidence) Created: 30 Apr 2024, 9:30 a.m. Panel version: 1.70 … kjt dortmund nathanWebUncoordinated-119 (Unc-119) is a protein that has been identified in C. elegans, humans, mice, zebrafish, rabbits, pig, calf, monkey, and protozoa. [5] They have been classified in … kjt new coachWebunc-13 homolog A (C. elegans) Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Essential ... kjt photographyWebThis gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, … recursion explained simply